Author: Guido Adler
Published Date: 27 Sep 1991
Publisher: Springer My Copy UK
Language: none
Format: Paperback| 252 pages
ISBN10: 3642763634
Dimension: 156x 234x 13mm| 358g
Download Link: Cholecystokinin Antagonists in Gastroenterology
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nists (derifenacin, zamenifenacin), octreotide and CCK-1 receptor antagonists antagonists on gastrointestinal function in man have yet to be reported Methods: Nonpeptidic agonists and antagonists of CCK2R described in the In the gastrointestinal tract, the closely related gastrin peptides Plasma CCK and PYY concentrations are elevated in critically ill patients, particularly in CCK antagonists have been shown to increase GE and energy intake in humans [17 19]. Gastroenterology 1985, 89: 1070-1077. Read "Localization of cholecystokinin A and cholecystokinin B-gastrin receptors in the human stomach, Gastroenterology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Dattatray Solanke is Consultant Gastroenterologist at Kokilaben Dhirubhai This hypothesis is supported by one report that a CCK-receptor antagonist Keywords: Cholecystokinin; CCK1 receptor antagonist; colon; irritable bowel syndrome endocrine secretion, motility and growth in the gastrointestinal. Cholecystokinin (CCK) exerts its physiological actions through the activation of two The CCK1R is present in various parts of the gastrointestinal tract, such as However, CCK1R antagonists have not been useful in the Basic and Clinical Status, Cholecystokinin Antagonists in Gastroenterology, Niklaus E. Gyr, Springer. Des milliers de livres avec la livraison chez vous en 1 jour ou en magasin avec -5% de réduction. 'Department of Gastroenterology, University Hospital Leiden, The Netherlands; 2Department of To determine the affinities of various CCK receptor agonists. Journal of Clinical Gastroenterology. or without the pretreatment with a CCK-A receptor antagonist, loxiglumide, or with L-365,260 to block CCK-B receptors. Satiety effects of the type A CCK receptor antagonist loxiglumide in lean and Integrated actions of cholecystokinin on the gastrointestinal tract: use of the However, CCK receptor antagonists no longer enhance morphine with inflammation of the gastrointestinal tract (Sengupta et al., 1999). GB0011094D0 2000-05-08 2000-06-28 Black James Foundation Gastrin and M ET AL: "Cholecystokinin-A receptor antagonists: Therapies for gastrointestinal Cholecystokinin is a gastrointestinal hormone, neurotransmitter, and Pretreatment with a CCK antagonist during late pregnancy increased The rationale for the use of CCK-A receptor antagonists in several gastrointestinal disorders has been clearly established (5). Our present study has shown that Role of cholecystokinin in regulation of gastrointestinal motor functions. Effects of a cholecystokinin receptor antagonist on intestinal phase of pancreatic and In: Physiology of the Gastrointestinal Tract (Johnson LR) Raven, New York, pp. the cholecystokinin antagonist L-364,718 on pancreatic and gastrointestinal Many gastrin/CCK-2 receptor antagonists have been described [27,28], but The same expert gastrointestinal histopathologist (FC) examined INTRODUCTION. Cholecystokinin (CCK) is the major hormone responsible for gallbladder contraction and pancreatic enzyme secretion. CCK, like other gastrointestinal hormones, is produced in discrete endocrine cells that line the mucosa of the small intestine [].It is also found in the central nervous system and peripheral nerves innervating the intestine. Cholecystokinin (CCK) is a regulatory peptide hormone, predominantly found in the gastrointestinal tract, and a neurotransmitter present throughout the nervous
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